MD Anderson Cancer Hospital: Locations and How to Get There
Mapping Your Path to MD Anderson’s Facilities
If you’re traveling to Houston for MD Anderson care, the hardest part of “getting there” is usually not the drive, it’s making sure you arrive at the right building with the least stress possible.
MD Anderson has a major campus inside the Texas Medical Center (TMC), plus several Greater Houston locations and a few specialty clinics. This guide helps you quickly identify where you need to go, how to get there (car, rideshare, rail, or airport arrival), and what to plan for on appointment days.
Important: Always follow the location details in your appointment confirmation or MyChart instructions first.
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Handpicked private estates ideal for extended stays near the Texas Medical Center.
Quick answer: which MD Anderson location should you go to?
Most visitors are headed to MD Anderson’s Texas Medical Center campus in Houston, but not always.
If your paperwork says “Texas Medical Center” (Holcombe/Pressler/Fannin): you’re likely headed to the main campus.
If it says League City, The Woodlands, Sugar Land, or West Houston: go directly to that Houston-area location.
If it mentions Proton Therapy or a specialty clinic name: confirm the specific address (these are often not at 1515 Holcombe).
Quick location list (addresses)
Texas Medical Center (Main Campus)
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Main Building:
📍 1515 Holcombe Blvd., Houston, TX 77030 -
Mays Clinic:
📍 1220 Holcombe Blvd., Houston, TX 77030 -
Duncan Building:
📍 1155 Pressler St., Houston, TX 77030 -
Radiology Outpatient Center (ROC):
📍 1700 Holcombe Blvd., Houston, TX 77030 -
Fannin Tower:
📍 6624 Fannin St., Houston, TX 77030
Greater Houston Locations
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League City:
📍 2280 Gulf Freeway South, League City, TX 77573 -
The Woodlands:
📍 100 Fellowship Drive, Conroe, TX 77384 -
Sugar Land:
📍 1327 Lake Pointe Parkway, Sugar Land, TX 77478 -
West Houston:
📍 13900 Katy Freeway, Houston, TX 77079
Step 1: confirm your destination
This takes 60 seconds and prevents most “wrong building” problems.
Check the address in your appointment confirmation (not only “MD Anderson”).
Save it in your maps app and keep it ready for rideshare drivers.
If you’re headed to the Texas Medical Center campus, confirm whether your appointment is in the Main Building, Mays Clinic, Duncan, ROC, or another site—each has different entrances and garages.
For longer stays, knowing your primary location also helps you choose the right area to live. Start here: Guide to MD Anderson patient lodging options in Houston.
Texas Medical Center campus: key buildings and addresses
When someone says “MD Anderson Houston,” they usually mean the Texas Medical Center campus. The campus is walkable, but it’s made up of multiple buildings—so use the building address in your navigation.
How to get to the Texas Medical Center campus
By car or rideshare
Enter the exact building address (not a general “MD Anderson” search result).
If you’re arriving during peak traffic, build extra buffer time for garage navigation.
By rail (METRORail)
METRO’s Red Line connects downtown Houston and the Texas Medical Center area. Depending on where you’re headed, stations include the TMC Transit Center and nearby stops.
Getting around inside Texas Medical Center
Texas Medical Center operates shuttle routes across the district on weekdays (routes/hours vary).
MD Anderson locations across Greater Houston
MD Anderson provides care at several Houston-area locations beyond the Texas Medical Center campus. These sites can be easier for parking and access when your care team schedules you there.
League City, TX 77573 The Woodlands 100 Fellowship Dr,
Conroe, TX 77384 Sugar Land 1327 Lake Pointe Pkwy,
Sugar Land, TX 77478 West Houston 13900 Katy Fwy,
Houston, TX 77079
Specialty clinics and centers
Getting to MD Anderson from Houston airports
Houston has two primary airports:
George Bush Intercontinental Airport (IAH) (north Houston)
William P. Hobby Airport (HOU) (southeast Houston)
Most visitors use:
Rideshare (Uber/Lyft)
Taxi
Rental car
Pre-arranged private car service
If you’re specifically searching for a shuttle option, read: Is there a shuttle from Houston Airport to MD Anderson?. Hotel shuttles (when available) vary by route and hours, so confirm details in advance.
For airport planning and lodging strategy, you may also find this useful: Which Houston airport is closer to MD Anderson?.
Arrival tips: parking, drop-off, timing
A few simple habits can make appointment days easier:
Choose the easiest route, not the “shortest.” Predictability matters when energy is limited.
Save the address and building name in your phone (and consider a screenshot of appointment details).
Plan a calm first day if you’re arriving from the airport, many families check into lodging first, then do a test drive to the clinic area.
If you’re arranging longer lodging, these guides can help you choose faster:
Where to stay near MD Anderson
Your care comes first—but your housing can make the routine lighter.
Short visits: hotels can be convenient
Longer visits (30+ days): furnished homes or apartments often provide the most comfort—kitchen, laundry, privacy, and space for caregivers
If you’re comparing options, start here:
Guide to MD Anderson patient lodging options in Houston
And explore Luxurway’s longer-stay options:
MD Anderson lodging • Houston rentals
FAQ
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A commonly referenced main building address is 1515 Holcombe Blvd., Houston, TX 77030, but many patients go to other campus buildings, so always follow your appointment address.
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Yes. METRO’s Red Line serves the Texas Medical Center area, including the TMC Transit Center and nearby stations.
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Yes. In addition to the Texas Medical Center campus, MD Anderson offers several Greater Houston locations, plus specialty clinics.
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Many families prefer a furnished home or apartment near the Texas Medical Center for longer visits (kitchen, laundry, privacy, and a calmer routine). Start with our lodging guide.
Simplifying Your Commute to Cancer Care
MD Anderson care in Houston often means the Texas Medical Center campus, but not always. The simplest way to reduce stress is to confirm your appointment address, save it in your navigation app, and plan a predictable arrival routine.
Once you know which location you’re headed to, everything else gets easier: airport planning, transportation choices, and (for longer visits) choosing a comfortable place to stay.
If you need a quiet, private place to stay near MD Anderson for an extended visit, Luxurway offers fully furnished homes and apartments designed for longer stays.