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What to Know about MD Anderson's Mays Clinic Cancer Care

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A Guide to Care at the Mays Clinic

This page is campus notes for the Mays Clinic. It is not housing. Confirm your appointment building first. The Mays Clinic is an outpatient building in the Texas Medical Center, with services such as the Breast Center, diagnostic imaging, and radiation oncology.

Luxurway also rents furnished homes near the Texas Medical Center if you need somewhere to stay.

However, the sheer size of the Texas Medical Center can be overwhelming. From finding the correct parking garage to securing a comfortable place to stay for weeks or months, the logistics can add unnecessary stress to your treatment.

At Luxurway, we specialize in providing private, fully furnished homes for MD Anderson patients. We understand that after a long day of appointments, you need more than a hotel room, you need a home. This guide covers everything you need to know about the Mays Clinic, ensuring your focus remains where it belongs: on your health and recovery.

Mays Clinic at a Glance (Quick Reference)

For patients in a rush, here are the essential facts you need to know before you head out the door.

CategoryDetails
Official Address1220 Holcombe Blvd, Houston, TX 77030
Main FunctionsOutpatient care, Breast Center, Diagnostic Imaging, Radiation Oncology, Cancer Prevention.
Parking and Drop-offMays Clinic Garage: Entrance 5 for self-parking. Entrance 7 is listed for patient drop-off; check current directions before traveling.
Connected BuildingsConnected via Skybridge to the Main Building and Duncan Building.
Furnished HousingLuxurway private homes for stays of 30 nights or longer. Compare each property’s location with your appointment building.

Parking details checked September 7, 2026: the Mays Clinic/Duncan Building garage is open 24 hours, with published charges from $3 for up to one hour to $13 for up to 24 hours. Mays Clinic valet operates Monday through Friday, 5 a.m.–11 p.m. with a published $20 flat fee. Check MD Anderson’s parking page for current hours and charges, and its entrance guide for directions before traveling.

What is the Mays Clinic?

The Lowry and Peggy Mays Clinic, opened in 2006, is a separate building from the Main Building (Alkek Hospital), though they are connected via a skybridge system. It was designed specifically to separate outpatient services from inpatient hospital activities, creating a more streamlined and less clinical environment for patients coming in for daily treatments or consultations.

Architecture Designed for Healing

The Mays Clinic is known for its "Tree Sculpture" in the lobby and ample natural light. The design philosophy was to create a calming atmosphere that reduces the "hospital feel." You will find:

  • The Tree of Life: A massive sculpture in the atrium that serves as a common meeting point.

  • Compassionate Amenities: The site includes a café, a pharmacy, and the "Place.. of wellness" which offers complementary therapies like yoga and massage for patients.

How it Differs from the Main Building

  • Main Building (1515 Holcombe): Primarily for surgeries, inpatient stays (overnight), and emergency care.

  • Mays Clinic (1220 Holcombe): Primarily for diagnostics (CT/MRI), chemotherapy infusions, radiation therapy, and clinic appointments.

Read More: Exploring MD Anderson Cancer Center Locations


Key Departments and Services

The Mays Clinic houses several critical centers. Knowing which building your appointment is in is vital, as walking from the Main Building to the Mays Clinic can take 15–20 minutes for those with limited mobility.

1. The Nellie B. Connally Breast Center

One of the largest centers within the Mays Clinic, this department offers multidisciplinary care for breast cancer patients. It allows patients to see surgeons, oncologists, and radiologists often in a single visit, reducing the need for multiple trips.

2. Diagnostic Imaging Center

If your schedule says "DI" or "Imaging," you will likely be here. This center is equipped with state-of-the-art MRI, CT, and PET scan machines.

  • Tip: Imaging appointments can run long. Bring a sweater (it is often cold) and a book or tablet.

3. Radiation Oncology

Located on the lower levels, this department uses advanced linear accelerators for precision radiation therapy. Because radiation treatments often require daily visits for 4–6 weeks, convenience and parking become major factors in your daily routine.

4. Cancer Prevention Center

Focused on screening and early detection, this center is for individuals who may have a high genetic risk or need preventive check-ups.


Navigating the Mays Clinic: Parking & Valet

Parking in the Texas Medical Center is notorious for being confusing. The Mays Clinic has its own dedicated parking infrastructure, which is distinct from the Main Building’s "Garage 10."

Self-Parking: The Mays Clinic Garage

  • Entrance: MD Anderson’s entrance guide lists Entrance 5 for Mays Clinic self-parking. Use the hospital’s current directions for your appointment building.
  • Hours and cost: The Mays Clinic/Duncan Building garage is open 24 hours. Published charges are $3 for up to one hour through $13 for up to 24 hours.

Valet Parking

Drop-off:The entrance guide lists Entrance 7 for patient drop-off. Follow current hospital signs and instructions for valet service.
Hours and cost:Mays Clinic valet operates Monday through Friday, 5 a.m.–11 p.m. with a published $20 flat fee.
Longer stays:Ask the parking office about current options for repeated visits.

These details were checked September 7, 2026 against MD Anderson’s parking page and entrance guide. Recheck hours, charges, and directions before traveling.

Read More: MD Anderson Places to Stay, Facilities, Parking for Visitors


Preparing for Your First Visit

Your first appointment at the Mays Clinic will likely be a consultation or a diagnostic day. To ensure it runs smoothly, preparation is key.

What to Bring Checklist

Medical Records:Physical copies of discs/scans if they haven't been digitally transferred yet.
Medication List:A printed list of all current dosages.
Comfort Items:The clinic is kept cool to protect equipment. Bring a warm blanket or hoodie.
Snacks/Water:While there are cafes (like the bistro on Floor 2), appointments can run late, and having water on hand is essential.
Notebook:You will receive a lot of information. Write down questions before you enter the room.

The "MyChart" App

MD Anderson uses MyChart for all schedules and test results. Download this app before you arrive. It frequently updates with "Wayfinding" maps that can guide you turn-by-turn inside the building.

Read More: Tips for your MD Anderson visit as a patient or family member


Where to Stay: Housing Options Near Mays Clinic

If your treatment at the Mays Clinic involves daily radiation or regular chemotherapy, you may be in Houston for several weeks or months. Choosing the right accommodation is just as important as choosing the right doctor.

While directories like Joe’s House list various hotels and discounted motels, many patients find that extended stays in hotels lack the privacy, space, and sanitation required for immunocompromised individuals.

Why Luxurway is the Preferred Choice for Mays Clinic Patients

Luxurway offers private, fully furnished single-family homes and spacious apartments specifically curated for medical patients. Here is how we compare to standard hotel options:

1. Proximity to Mays Clinic

Luxurway offers homes in several Houston neighborhoods. Travel time to Mays Clinic depends on the property, traffic, and your appointment building. Compare the home’s location and check a current route before booking.

  • Avoid the Highway: Our locations allow you to take surface streets, avoiding the stress of Houston freeway traffic.

2. Private Kitchens for Dietary Needs

Chemotherapy often changes your appetite or requires strict dietary restrictions.

  • Hotels: Mini-fridges and microwaves limit your ability to eat healthy.

  • Luxurway: Full gourmet kitchens allow caregivers to prepare fresh, specific meals that aid in recovery.

3. Immune-Friendly Environments

In a hotel, you share elevators, lobbies, and HVAC systems with hundreds of travelers.

  • Luxurway: You rent a private home. No shared lobbies, no crowded elevators, and control over your own environment. This is critical for patients with low white blood cell counts.

4. Space for Caregivers

Treatment is rarely a solo journey. Family members need space to work, relax, and sleep without disturbing the patient. Our homes feature multiple bedrooms, private backyards, and spacious living areas.

FeatureLuxurway Private HousingExtended Stay HotelsJoe's House / Budget Motels
PrivacyHigh (Private Home)Medium (Shared Walls)Low (High Traffic)
KitchenFull Chef's KitchenKitchenetteNone / Microwave
CleanlinessDeep Cleaned per GuestDaily Maid ServiceVariable
ParkingPrivate Garage/DrivewayShared Lot (Often Paid)Shared Lot
CostCost-Effective for Long StaysHigh Daily RatesBudget Friendly

Read More: MD Anderson Housing and Lodging 101


Comprehensive Support for Your Mays Clinic Visit

The Mays Clinic at MD Anderson represents the pinnacle of cancer care, designed to make outpatient treatment as effective and comfortable as possible. By understanding the layout, planning your parking strategy, and securing the right environment for your rest and recovery, you can remove the logistical burdens of your journey.

Your focus should be on healing. Let us handle the housing.

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